Entry Detail



General Information

Database ID:exR0358772
RNA Name:hsa-miR-129-2-3p
RNA Type:miRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):43581450End Site(bp):43581471
External Links:hsa-miR-129-2-3p



Disease Information

Disease Name:Newborn Infant
Disease Category:Other Diseases
MeSH ID:D007231
Type:Age Groups/Infant
Alias:Infant, Newborn//Infants, Newborn//Newborn Infant//Newborn Infants//Newborns//Newborn//Neonate//Neonates



Expression Detail

GEO ID:GSE65203
Description:microRNA as a new immune-regulatory agent in breast milk
Experimental Design:Disease vs Control
Case Disease Type:Newborn Infant
Case Disease SubType:NA
Case Sample:Deliver < 28 days
Control Sample:Deliver > 28 days
Number of Case:2
Number of Control:4
Number of Samples:6





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGTRAP
chr1
11736084
11754802
+
PRDM15
chr21
41798225
41879482
-
SLC25A25
chr9
128068201
128109245
+
TSC22D2
chr3
150408335
150466431
+
TUB
chr11
8019244
8106112
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001146
chr20
34241449
34246936
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005394.2
chr19
28435388
28727680
-
AC104794.2
chr2
10083781
10086101
+
AC145207.5
chr17
81878425
81881106
-
AL132655.2
chr20
58817132
58817725
-
AL360012.1
chr1
28648600
28648730
+
HCG11
chr6
26521709
26527404
+
KCNQ1OT1
chr11
2608328
2699994
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG12
chr1
28578538
28583132
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE65203
Sample Source:Breast Milk
Source Fraction:Supernatant
Platform:GPL7731
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:548
Sample treatment protocol:NA
RNA Extract protocol:Total RNA extracted using mirVana miRNA isolation kit following manufacturer's instructions.
RNA library preparation protocol:70 ng of each RNA sample was labeled with the miRNA Complete Labeling Reagent and Hybridization kit (Agilent Technologies) according to the manufacturer's instructions.



Reference

PMID:20226005
Title:microRNA as a new immune-regulatory agent in breast milk
Author:Kosaka N, Izumi H, Sekine K, Ochiya T.
Journal:Silence. 2010 Mar 1;1(1):7.
Description:BACKGROUND: Breast milk is a complex liquid that provides nutrition to the infant and facilitates the maturation of the infant's immune system. Recent studies indicated that microRNA (miRNA) exists in human body fluid. Because miRNAs are known to regulate various immune systems, we hypothesized that human breast milk contains miRNAs that may be important for the development of the infant's immune system.