exRNAdisease

Entry Detail

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General Information

Database ID: exR0428562 RNA Name: AAGAB RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 67200667 End Site(bp): 67255195 External Links: ENSG00000103591

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BTBD1 chr15 83016423 83067252 - PIMREG chr17 6444441 6451469 + HNRNPA1 chr12 54280193 54287088 + SETD1A chr16 30957754 30984664 + RAC3 chr17 82031678 82034204 + ARF4 chr3 57571363 57598220 - RPL27 chr17 42998273 43002959 + HSDL1 chr16 84122141 84145192 - CHD7 chr8 60678740 60868028 + CRABP2 chr1 156699606 156705816 - DUT chr15 48331011 48343373 + UNC119B chr12 120710458 120723640 + PRDM2 chr1 13700198 13825079 + BCAP31 chrX 153700492 153724565 - TOMM20 chr1 235109341 235128837 - CDPF1 chr22 46244011 46250311 - MRPL45 chr17 38297023 38323217 + CHMP3 chr2 86503430 86563479 - RPS23 chr5 82273320 82278396 - RTN4 chr2 54972187 55112621 - CCND2 chr12 4273762 4305353 + FUS chr16 31180110 31194871 + YWHAQ chr2 9583967 9630997 - PFN1 chr17 4945652 4949061 - GPAM chr10 112149865 112215377 - HYAL2 chr3 50317790 50322782 - R3HDM1 chr2 135531455 135725270 + FTL chr19 48965309 48966879 + RPL10A chr6 35468401 35470785 + RIC1 chr9 5629025 5776557 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand HLA-F-AS1 chr6 29726601 29749049 - PARD6G-AS1 chr18 80147924 80179839 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.