exRNAdisease

Entry Detail

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General Information

Database ID: exR0428570 RNA Name: AARSD1 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 42950526 End Site(bp): 42964498 External Links: ENSG00000266967

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PTMS chr12 6765516 6770952 + KBTBD7 chr13 41189834 41194569 - PPDPF chr20 63520765 63522206 + PPP1CC chr12 110719680 110742939 - BLOC1S5-TXNDC5 chr6 7881522 8064364 - ZNF777 chr7 149431363 149461062 - CALM3 chr19 46601074 46610782 + HIGD2A chr5 176388751 176389761 + RPL35A chr3 197950190 197956610 + HNRNPF chr10 43385617 43409166 - CCNT2 chr2 134918235 134959342 + ERI2 chr16 20780193 20900349 - RPUSD3 chr3 9837849 9844602 - TPT1 chr13 45333471 45341370 - RNPS1 chr16 2253116 2268397 - CALR chr19 12938578 12944489 + PTGES3L-AARSD1 chr17 42950526 42980528 - RNF213 chr17 80260866 80398786 + SASH3 chrX 129779949 129795201 + EDARADD chr1 236348257 236502915 + CST3 chr20 23626706 23638473 - SKI chr1 2228319 2310213 + MRPL13 chr8 120380761 120445402 - TMEM258 chr11 61768501 61792802 - ASB8 chr12 48147789 48181213 - RPL27 chr17 42998273 43002959 + GSPT2 chrX 51743442 51746232 + TXNDC5 chr6 7881517 7910788 - DYNLL1 chr12 120469850 120498493 + TRMU chr22 46330875 46357340 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand Z95114.1 chr22 36071000 36085573 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.