exRNAdisease

Entry Detail

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General Information

Database ID: exR0428585 RNA Name: ABCA7 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 1039997 End Site(bp): 1065572 External Links: ENSG00000064687

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008982.1 chr19 38817471 38840178 - AGPAT2 chr9 136673143 136687457 - ANP32E chr1 150218417 150236156 - ATP2B4 chr1 203626561 203744081 + CCNE1 chr19 29811991 29824312 + CD99 chrX 2691187 2741309 + EIF4G3 chr1 20806292 21176888 - FAM50A chrX 154444141 154450654 + GNB1 chr1 1785285 1891117 - HMGXB3 chr5 150000046 150053142 + HNRNPL chr19 38836388 38852347 - ILF3 chr19 10654261 10692417 + LRRK1 chr15 100919327 101078257 + MDH2 chr7 76048051 76067508 + METTL24 chr6 110245928 110358272 - MPG chr16 77007 85853 + MT-CO1 chrMT 5904 7445 + MTRNR2L8 chr11 10507894 10509186 - PARP6 chr15 72241181 72272999 - SLC29A2 chr11 66362521 66372214 - SNX17 chr2 27370496 27377535 + SRSF1 chr17 58000919 58007346 - TMCO3 chr13 113491021 113554590 + TMEM201 chr1 9588911 9614877 + TMEM69 chr1 45688181 45694436 + TNKS chr8 9555912 9782346 + TSPAN3 chr15 77041404 77083984 - TUBA1A chr12 49184795 49189080 - ZNF200 chr16 3222325 3236221 - ZNF800 chr7 127346790 127431924 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC01783 chr1 16533886 16536172 - SNHG17 chr20 38419638 38435409 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.