exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428589 RNA Name: ABCB10 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 229516582 End Site(bp): 229558707 External Links: ENSG00000135776

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PKN1 chr19 14433053 14471867 + HELQ chr4 83407343 83455855 - MBOAT7 chr19 54173412 54189882 - RPL32 chr3 12834485 12841582 - DUSP16 chr12 12473282 12562863 - CBX6 chr22 38861422 38872249 - FOXK1 chr7 4682295 4771442 + NISCH chr3 52455118 52493068 + MTA1 chr14 105419820 105470729 + METTL9 chr16 21597218 21657473 + ESPL1 chr12 53268299 53293638 + NPHP4 chr1 5862811 5992473 - GAREM1 chr18 32124877 32470882 - RPS3 chr11 75399515 75422280 + NELL2 chr12 44508275 44921848 - VPS13D chr1 12230030 12512047 + BRWD1 chr21 39184176 39321559 - PRELID1 chr5 177303799 177306949 + NAT10 chr11 34105617 34147670 + HTATSF1 chrX 136497079 136512346 + GAN chr16 81314966 81380198 + PUS3 chr11 125893485 125903221 - CLPTM1 chr19 44954585 44993341 + DPP9 chr19 4675224 4724673 - CCZ1 chr7 5898725 5926550 + SLC37A4 chr11 119024114 119030906 - MLEC chr12 120687149 120701859 + BRSK2 chr11 1389899 1462689 + MAP4 chr3 47850690 48089272 - PI4KB chr1 151291797 151327715 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG4 chr5 139274102 139284899 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.