exRNAdisease

Entry Detail

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General Information

Database ID: exR0428590 RNA Name: ABCB4 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 87401697 End Site(bp): 87480435 External Links: ENSG00000005471

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB1 chr7 87503017 87713323 - AP1G2 chr14 23559565 23568070 - BASP1 chr5 17065598 17276843 + CENPV chr17 16342534 16353656 - CLDN6 chr16 3014712 3020071 - CUL5 chr11 108008898 108107761 + DDX5 chr17 64498254 64508199 - EIF5A chr17 7306999 7312463 + FXR2 chr17 7591230 7614897 - HNRNPDL chr4 82422564 82430408 - HSPA8 chr11 123057489 123063230 - HTATSF1 chrX 136497079 136512346 + KIF5B chr10 32009015 32056425 - MAF1 chr8 144104461 144107611 + NUAK1 chr12 106063340 106140033 - PAM chr5 102753981 103031105 + PHF14 chr7 10973336 11169630 + RPL5 chr1 92832013 92841924 + SERF2 chr15 43777087 43802589 + SLC39A1 chr1 153959099 153968184 - SNX18 chr5 54517759 54546586 + SPOCK2 chr10 72059034 72089032 - STX7 chr6 132445867 132513198 - TMEM167A chr5 83052846 83077863 - TPT1 chr13 45333471 45341370 - ZNF136 chr19 12163064 12189871 + ZNF385A chr12 54369133 54391298 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.