exRNAdisease

Entry Detail

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General Information

Database ID: exR0428592 RNA Name: ABCB6 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 219209772 End Site(bp): 219218994 External Links: ENSG00000115657

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CLCN5 chrX 49922596 50099235 + CHMP1A chr16 89644435 89657721 - COA1 chr7 43608456 43729717 - PA2G4 chr12 56104537 56113910 + PYCR2 chr1 225919877 225924340 - HLA-E chr6 30489509 30494194 + SNRPD2 chr19 45687454 45692569 - GADD45GIP1 chr19 12953119 12957223 - VCL chr10 73995193 74121363 + SNRPD3 chr22 24555958 24582052 + FARSA chr19 12922479 12934037 - SMDT1 chr22 42079691 42084284 + EEF2 chr19 3976056 3985463 - POU3F3 chr2 104853287 104858574 + GRK2 chr11 67266473 67286556 + GAPDH chr12 6534512 6538374 + WSB1 chr17 27294076 27315926 + MYCBP2 chr13 77044657 77327094 - SAC3D1 chr11 65040901 65044828 + PPP4C chr16 30075978 30085376 + KRT7 chr12 52232520 52252186 + AC068946.2 chr2 219209772 219222738 - PTPRS chr19 5158495 5340803 - SETD1B chr12 121804180 121832584 + ARID1B chr6 156776020 157210779 + CAMK2G chr10 73812501 73874591 - POU6F1 chr12 51186936 51217708 - PFN1 chr17 4945652 4949061 - LAMP1 chr13 113297239 113323672 + RAD51D chr17 35092208 35121522 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.