exRNAdisease

Entry Detail

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General Information

Database ID: exR0428593 RNA Name: ABCB7 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 75051048 End Site(bp): 75156732 External Links: ENSG00000131269

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand YWHAZ chr8 100916523 100953388 - DDX5 chr17 64498254 64508199 - MAPKAPK2 chr1 206684944 206734283 + YWHAQ chr2 9583967 9630997 - MT-CO1 chrMT 5904 7445 + CSNK2B chr6 31665236 31670343 + MAGED1 chrX 51803007 51902357 + PBX2 chr6 32184733 32190202 - CCNI chr4 77047155 77075989 - CFL1 chr11 65823022 65862026 - TM7SF3 chr12 26971579 27014434 - ADD1 chr4 2843857 2930076 + AP002990.1 chr11 62559603 62591531 - RARA chr17 40309180 40357643 + RPAIN chr17 5419641 5432876 + RPS12 chr6 132814569 132817564 + IPO5 chr13 97953658 98024296 + NOMO3 chr16 16232528 16294811 + JMJD1C chr10 63167221 63521850 - MEN1 chr11 64803510 64811294 - RAB11A chr15 65726054 65891989 + P4HB chr17 81843161 81860624 - EEF1G chr11 62559596 62574086 - TMSB4X chrX 12975110 12977227 + CAPN15 chr16 527712 554636 + RABEP1 chr17 5282265 5386340 + LPCAT1 chr5 1456480 1523962 - INSIG1 chr7 155297776 155310235 + ANP32B chr9 97983341 98015943 + TMED5 chr1 93149742 93180516 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand EBLN3P chr9 37079645 37090928 + LINC00205 chr21 45288050 45297806 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.