Entry Detail



General Information

Database ID:exR0428595
RNA Name:ABCB9
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):122920951End Site(bp):122981649
External Links:ENSG00000150967



Disease Information

Disease Name:Pediatric TB meningitis
Disease Category:Infections
MeSH ID:D014390
Type:Diseases Category/Infections
Alias:Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Pediatric TB meningitis
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CS
chr12
56271699
56300391
-
EIF3C
chr16
28688558
28735730
+
EPB41L4B
chr9
109171975
109320964
-
ERF
chr19
42247569
42255128
-
FAU
chr11
65120630
65122177
-
FOXRED2
chr22
36487190
36507101
-
LARP1
chr5
154712843
154817605
+
LCOR
chr10
96832282
96995959
+
LMO2
chr11
33858576
33892076
-
PAQR4
chr16
2969270
2973484
+
PVR
chr19
44643798
44666162
+
SNRPD3
chr22
24555958
24582052
+
TCF25
chr16
89873570
89913627
+
TMEM259
chr19
1009648
1021179
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245014.3
chr1
145281116
145281462
+
AC079949.1
chr12
127142029
127146532
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.