exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428596 RNA Name: ABCC1 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 15949577 End Site(bp): 16143074 External Links: ENSG00000103222

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TMED2 chr12 123584533 123598582 + PCDHGB6 chr5 141408021 141512979 + ADGRV1 chr5 90529344 91164437 + CENPU chr4 184694085 184734130 - RFC5 chr12 118013588 118033130 + BLVRB chr19 40447765 40465764 - MACF1 chr1 39081316 39487177 + RPS5 chr19 58386400 58394806 + SETD1A chr16 30957754 30984664 + CRTC3 chr15 90529923 90645345 + PCDHGB1 chr5 141350102 141512979 + PCDHGA8 chr5 141390157 141512979 + NUCKS1 chr1 205712822 205750182 - MT-ND4 chrMT 10760 12137 + ASXL1 chr20 32358330 32439319 + STRBP chr9 123109500 123268586 - UBE2S chr19 55399745 55407788 - ZDHHC4 chr7 6577434 6589374 + NOP53 chr19 47745546 47757058 + CD52 chr1 26317958 26320523 + PSMB9 chr6 32844136 32859851 + PCDHGA7 chr5 141382739 141512975 + MT-CYB chrMT 14747 15887 + MT-ND5 chrMT 12337 14148 + PCDHGA6 chr5 141373914 141512979 + PCDHGA5 chr5 141364232 141512979 + EIF4G2 chr11 10797050 10808940 - MT-CO2 chrMT 7586 8269 + SC5D chr11 121292681 121313410 + AC104109.3 chr5 134167170 134226071 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL136419.1 chr14 23969931 24051377 + AC138932.3 chr16 14909887 14911345 - ERVK13-1 chr16 2660348 2682379 - GAS5 chr1 173858559 173868882 - MIR663AHG chr20 26167817 26251546 - SNHG17 chr20 38419638 38435409 - SNHG19 chr16 2154797 2155358 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.