exRNAdisease

Entry Detail

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General Information

Database ID: exR0428597 RNA Name: ABCC10 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 43427366 End Site(bp): 43450427 External Links: ENSG00000124574

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GTPBP1 chr22 38705742 38738299 + PUM1 chr1 30931506 31065991 - ELMSAN1 chr14 73715122 73790285 - ZNF462 chr9 106863166 107013634 + RPL13 chr16 89560657 89566828 + DIP2A chr21 46458891 46570015 + YWHAG chr7 76326799 76358991 - DNMT1 chr19 10133345 10231286 - ERCC2 chr19 45349837 45370918 - EGFL7 chr9 136658856 136672678 + MAP3K11 chr11 65597756 65615382 - RPL18A chr19 17859910 17864153 + CLEC2D chr12 9664969 9699553 + SPATA20 chr17 50543058 50555852 + SLC12A9 chr7 100826820 100867010 + DYRK2 chr12 67648338 67665406 + SF3A2 chr19 2236824 2248655 + NCOA6 chr20 34689097 34825651 - PLCG1 chr20 41136960 41196801 + FBN2 chr5 128257909 128659185 - MCCC2 chr5 71587288 71658706 + AP5B1 chr11 65773898 65780976 - UBAC1 chr9 135932969 135961373 - MMADHC chr2 149569637 149587778 - PKMYT1 chr16 2968024 2980479 - UGP2 chr2 63840940 63891562 + FAM3A chrX 154506159 154516242 - NOTCH2 chr1 119911553 120100779 - IMP3 chr15 75639085 75648706 - PHGDH chr1 119648411 119744226 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6780b-3p chr6 43434600 43434620 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC092139.1 chr16 81385463 81387560 + AP001266.1 chr11 65795946 65797219 - LINC01248 chr2 5602505 5691488 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.