exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428602 RNA Name: ABCC4 RNA Type: mRNA Chromosome: chr13 Starnd: - Coordinate: Start Site(bp): 95019835 End Site(bp): 95301475 External Links: ENSG00000125257

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand KIF7 chr15 89608789 89655467 - ERFE chr2 238158970 238168900 + POLR3D chr8 22245133 22254601 + SLC5A6 chr2 27199587 27212958 - PIGC chr1 172370189 172444086 - AC007192.1 chr19 18153158 18178117 + NDUFA10 chr2 239892450 240025345 - ZBTB21 chr21 41986831 42010387 - RUVBL1 chr3 128064778 128153914 - ZDHHC20 chr13 21372573 21459370 - IFI6 chr1 27666064 27672198 - MYO1G chr7 44962662 44979088 - DPPA4 chr3 109326141 109337572 - CCT8 chr21 29055805 29073797 - BASP1 chr5 17065598 17276843 + FNBP1 chr9 129887187 130043194 - LTBP4 chr19 40592883 40629818 + LARP1 chr5 154712843 154817605 + RPL4 chr15 66498015 66524532 - RRM1 chr11 4094707 4138932 + SPOUT1 chr9 128819651 128829794 - LLGL2 chr17 75525080 75575208 + SACS chr13 23328826 23433740 - RPL27A chr11 8682788 8714759 + YIPF5 chr5 144158162 144170714 - SRP14 chr15 40035690 40039181 - FKBP8 chr19 18531751 18544077 - KMT2B chr19 35717973 35738878 + DDX41 chr5 177511577 177516961 - ING3 chr7 120950763 120977216 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand CRTC3-AS1 chr15 90620007 90717141 - DLEU1 chr13 50082169 50906856 + MALAT1 chr11 65497688 65506516 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.