exRNAdisease

Entry Detail

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General Information

Database ID: exR0428603 RNA Name: ABCC5 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 183919934 End Site(bp): 184017939 External Links: ENSG00000114770

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand VAPA chr18 9914002 9960021 + DGKQ chr4 958887 986895 - STRADA chr17 63682336 63741986 - POFUT1 chr20 32207880 32238658 + DSTN chr20 17570075 17609919 + EEF1D chr8 143579697 143599541 - STRA6 chr15 74179466 74212267 - WDR43 chr2 28894667 28948219 + TMEM63A chr1 225845536 225882380 - OBSL1 chr2 219550728 219571859 - RITA1 chr12 113185526 113192368 + MKRN1 chr7 140453033 140479536 - BSG chr19 571277 583493 + CALM3 chr19 46601074 46610782 + RPL37 chr5 40825262 40835222 - PLEKHG3 chr14 64704102 64750249 + SMAD4 chr18 51028394 51085045 + SNX5 chr20 17941597 17968980 - PPP2R3B chrX 333933 386955 - SCMH1 chr1 41027200 41242154 - LCK chr1 32251239 32286165 + SIK2 chr11 111602449 111730855 + PPP2R1B chr11 111726908 111766389 - SNX2 chr5 122775079 122834543 + KLHL23 chr2 169694488 169776989 + RAB4B-EGLN2 chr19 40778242 40808418 + WDR86 chr7 151375909 151410727 - REPS1 chr6 138903493 138988261 - PABPC3 chr13 25095868 25099254 + PROCA1 chr17 28703197 28711854 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1323 chr19 53671978 53671999 + hsa-miR-548o-3p chr20 38516607 38516628 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.