exRNAdisease

Entry Detail

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General Information

Database ID: exR0428612 RNA Name: ABCF1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 30571393 End Site(bp): 30597179 External Links: ENSG00000204574

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HLA-DRB1 chr6 32578769 32589848 - ZNF501 chr3 44729596 44737083 + TMEM250 chr9 136114581 136118875 - MT-CO1 chrMT 5904 7445 + GLUL chr1 182381704 182392206 - CIC chr19 42268537 42295797 + MTRNR2L8 chr11 10507894 10509186 - MYLIP chr6 16129086 16148248 + IFIT3 chr10 89327997 89340971 + ZNF581 chr19 55635459 55645623 + MAU2 chr19 19320829 19358754 + CERS2 chr1 150960583 150975004 - TNRC6A chr16 24610209 24827632 + PDP2 chr16 66878589 66895754 + BSG chr19 571277 583493 + EEF1G chr11 62559596 62574086 - PTBP1 chr19 797075 812327 + AP1S2 chrX 15825806 15854931 - FTL chr19 48965309 48966879 + IQGAP1 chr15 90388242 90502239 + SURF4 chr9 133361450 133376166 - SELENON chr1 25800176 25818221 + RPS6 chr9 19375715 19380236 - PDCD6IP chr3 33798571 33869707 + GPC6 chr13 93226807 94408020 + VPS26A chr10 69123512 69174412 + CYFIP2 chr5 157266079 157395595 + MFSD5 chr12 53251251 53254405 + AC005832.4 chr12 4604944 4662643 + BZW2 chr7 16646131 16706523 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC000068.1 chr22 19447893 19450105 + AC010642.2 chr19 58309727 58327248 - DANCR chr4 52712404 52720351 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.