exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428613 RNA Name: ABCF2 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 151207837 End Site(bp): 151227166 External Links: ENSG00000285292

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COX7C chr5 86617928 86620962 + ABCF2 chr7 151207837 151227166 - EIF3L chr22 37848868 37889407 + PROM1 chr4 15963076 16084378 - MTG1 chr10 133394094 133422520 + SPG11 chr15 44562696 44663678 - SUV39H2 chr10 14878820 14904315 + MAP4 chr3 47850690 48089272 - BTBD2 chr19 1985438 2034881 - TRAPPC12 chr2 3379675 3485094 + DYNLL2 chr17 58083419 58095542 + IL32 chr16 3065297 3082192 + STAT5B chr17 42199177 42276707 - RPS4X chrX 72255679 72277248 - MCOLN1 chr19 7522624 7534009 + OST4 chr2 27070472 27071654 - SERPINE1 chr7 101127104 101139247 + CCT4 chr2 61868085 61888671 - ENO1 chr1 8861000 8879190 - ELOVL5 chr6 53267398 53349179 - CD164 chr6 109366514 109382467 - SLC37A4 chr11 119024114 119030906 - AL360181.3 chr10 133380017 133420271 + PHIP chr6 78934419 79078254 - LPGAT1 chr1 211743457 211830763 - BCAT2 chr19 48795062 48811029 - UBB chr17 16380798 16382745 + ERMP1 chr9 5765076 5833117 - UBE2Q1 chr1 154548577 154559028 - SNRNP40 chr1 31259568 31296788 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005487.1 chr7 108598352 108639349 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.