exRNAdisease

Entry Detail

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General Information

Database ID: exR0428614 RNA Name: ABCF3 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 184186023 End Site(bp): 184194012 External Links: ENSG00000161204

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand STARD10 chr11 72754729 72793681 - TRIOBP chr22 37697048 37776556 + ABCF2 chr7 151207837 151227166 - AFDN chr6 167826922 167972023 + MBD5 chr2 148021011 148516971 + RARB chr3 25174332 25597932 + EPN3 chr17 50532682 50543750 + TPI1 chr12 6867119 6870948 + PPP1R16B chr20 38805697 38923024 + MATR3 chr5 139273752 139331671 + RAB43 chr3 129087569 129122801 - EXOC7 chr17 76081016 76121576 - SSR4 chrX 153793516 153798499 + RPS19 chr19 41860255 41872925 + ZEB2 chr2 144364364 144521057 - HOXD3 chr2 176136612 176173102 + KRR1 chr12 75490863 75511636 - LIG3 chr17 34980512 35009743 + Z83844.1 chr22 37686414 37726503 + RPL13 chr16 89560657 89566828 + SNRPG chr2 70281362 70293740 - EEF1A1 chr6 73515750 73523797 - PDCD7 chr15 65117379 65133808 - MAPKAP1 chr9 125437393 125707234 - RPS6 chr9 19375715 19380236 - GGA3 chr17 75236599 75262363 - RERE chr1 8352397 8848921 - SAT1 chrX 23783173 23786226 + MTRNR2L12 chr3 96617188 96618236 - MARCKSL1 chr1 32333839 32336233 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-497-5p chr17 7017979 7017999 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016949.1 chr3 196912646 196914579 + AL355075.4 chr14 20343048 20343685 - LINC00858 chr10 84267747 84294659 + RMRP chr9 35657751 35658018 - SRRM2-AS1 chr16 2737076 2752600 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.