exRNAdisease

Entry Detail

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General Information

Database ID: exR0428616 RNA Name: ABCG2 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 88090150 End Site(bp): 88231628 External Links: ENSG00000118777

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PTMS chr12 6765516 6770952 + AP2B1 chr17 35578046 35726413 + PFN1 chr17 4945652 4949061 - ACKR3 chr2 236567787 236582354 + RFX5 chr1 151340640 151347357 - SUPT16H chr14 21351476 21384019 - ABHD14A-ACY1 chr3 51974706 51989183 + PLXNA2 chr1 208022242 208244384 - PDXDC1 chr16 14974591 15139339 + SDC2 chr8 96493813 96611790 + MORN3 chr12 121648742 121672631 - RARB chr3 25174332 25597932 + GNPDA1 chr5 141991749 142013041 - TPT1 chr13 45333471 45341370 - ZNRF2 chr7 30284597 30367689 + PSMA5 chr1 109399042 109426448 - ELF1 chr13 40931924 41061440 - PDHB chr3 58427630 58433857 - PSMA4 chr15 78540405 78552417 + CCND3 chr6 41934933 42050357 - NELFA chr4 1982717 2041903 - RPS3 chr11 75399515 75422280 + MTRNR2L12 chr3 96617188 96618236 - NMD3 chr3 161104696 161253532 + UGT3A2 chr5 36035021 36071358 - AFF4 chr5 132875395 132963634 - HNRNPA2B1 chr7 26173057 26201529 - CDH1 chr16 68737292 68835541 + SIPA1L1 chr14 71320449 71741229 + RPL9 chr4 39452521 39458949 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC078881.1 chr4 177442519 177681381 + AC069287.1 chr11 112967 125927 - NR2F1-AS1 chr5 93360779 93585649 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.