exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428619 RNA Name: ABHD10 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 111979010 End Site(bp): 111993368 External Links: ENSG00000144827

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPN2 chr20 37178410 37241619 + STAC2 chr17 39210541 39225945 - GLUL chr1 182381704 182392206 - COL4A2 chr13 110305812 110513209 + YBX3 chr12 10699089 10723323 - CXCR4 chr2 136114349 136118149 - LBHD1 chr11 62662817 62672255 - PPIA chr7 44796680 44824564 + C11orf98 chr11 62662816 62665217 - RPL13 chr16 89560657 89566828 + MBD4 chr3 129430944 129440179 - MTRNR2L8 chr11 10507894 10509186 - DIDO1 chr20 62877738 62937952 - MYO1G chr7 44962662 44979088 - CTSZ chr20 58995185 59007254 - EEF1D chr8 143579697 143599541 - AP001458.2 chr11 62649694 62665178 - TBP chr6 170554302 170572870 + RPL3 chr22 39312882 39320389 - INTS12 chr4 105682627 105895986 - RPS23 chr5 82273320 82278396 - ATXN7 chr3 63864557 64003462 + MPP6 chr7 24573268 24694193 + RPS5 chr19 58386400 58394806 + RPL27A chr11 8682788 8714759 + TBC1D10B chr16 30357102 30370494 - TALDO1 chr11 747415 765012 + CLCN3 chr4 169612633 169723673 + ZNF277 chr7 112206695 112343934 + UBXN7 chr3 196347662 196432430 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.