exRNAdisease

Entry Detail

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General Information

Database ID: exR0428621 RNA Name: ABHD12 RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 25294742 End Site(bp): 25390835 External Links: ENSG00000100997

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NAT8L chr4 2059327 2069089 + MAN2A1 chr5 109689366 109869625 + CUTC chr10 99702558 99756134 + ERAL1 chr17 28855010 28861061 + HMOX1 chr22 35380361 35394207 + MSL2 chr3 136148917 136197241 - ERBB2 chr17 39687914 39730426 + RPL8 chr8 144789765 144792587 - MX1 chr21 41420304 41459214 + ACP6 chr1 147629652 147670524 - SIRT6 chr19 4174109 4182566 - LSM7 chr19 2321520 2328611 - PDCD2L chr19 34404399 34426168 + TPX2 chr20 31739271 31801805 + ZNF764 chr16 30553764 30558498 - TSPAN3 chr15 77041404 77083984 - CXADR chr21 17513043 17593579 + ARIH2 chr3 48918821 48986382 + RBM27 chr5 146203605 146289223 + GINS1 chr20 25407673 25452628 + UBE2J1 chr6 89326625 89352722 - RBM22 chr5 150690792 150701077 - EEF2 chr19 3976056 3985463 - MED16 chr19 867630 893218 - CYB5R3 chr22 42617840 42649392 - PHIP chr6 78934419 79078254 - RBFA chr18 80034389 80050651 + EIF2S2 chr20 34088309 34112243 - FKBP10 chr17 41812680 41823213 + EML4 chr2 42169353 42332548 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012236.1 chr15 31221999 31230838 - AD000090.1 chr19 35557956 35581954 + AL135925.1 chr10 79825902 79827602 + SNHG22 chr18 49814023 49851059 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.