exRNAdisease

Entry Detail

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General Information

Database ID: exR0428623 RNA Name: ABHD13 RNA Type: mRNA Chromosome: chr13 Starnd: + Coordinate: Start Site(bp): 108218392 End Site(bp): 108234243 External Links: ENSG00000139826

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKRD46 chr8 100509752 100559784 - ARMT1 chr6 151452258 151470101 + CCR7 chr17 40553769 40565472 - CHIC1 chrX 73563200 73687102 + CUL4A chr13 113208193 113267108 + HDAC2 chr6 113933028 114011308 - HSPA4 chr5 133052013 133106449 + IDH1 chr2 208236227 208266074 - LIN28A chr1 26410817 26429728 + MRI1 chr19 13764522 13774282 + MT-ND4 chrMT 10760 12137 + PPM1G chr2 27381195 27409591 - RAB18 chr10 27504174 27542237 + RAB7A chr3 128726183 128814798 + RCN2 chr15 76931738 76954393 + RHEB chr7 151466012 151520120 - RHOT1 chr17 32142454 32253374 + RNF138 chr18 32091874 32131561 + SCAMP3 chr1 155255979 155262430 - SSRP1 chr11 57325986 57335892 - STIM2 chr4 26857601 27025381 + SV2A chr1 149903318 149917844 - TRIP6 chr7 100867387 100873454 + U2AF1 chr21 43092956 43107587 - U2AF1L5 chr21 6484623 6499261 - UBR4 chr1 19074510 19210266 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.