exRNAdisease

Entry Detail

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General Information

Database ID: exR0428625 RNA Name: ABHD14B RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 51968510 End Site(bp): 51983409 External Links: ENSG00000114779

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FTL chr19 48965309 48966879 + SMARCD1 chr12 50085200 50100707 + UTP3 chr4 70688532 70690551 + RPL13A chr19 49487554 49492308 + NELFB chr9 137255327 137273542 + HLA-DPB1 chr6 33075990 33089696 + RIC8A chr11 207511 215113 + GATD1 chr11 767220 777488 - AC010422.3 chr19 12643831 12648397 - RTCA chr1 100266207 100292769 + CCDC86 chr11 60842113 60851081 + ZNF160 chr19 53066606 53103436 - RHOA chr3 49359145 49412998 - RPL37 chr5 40825262 40835222 - EEF2 chr19 3976056 3985463 - RPS6 chr9 19375715 19380236 - JOSD2 chr19 50505998 50511353 - SSRP1 chr11 57325986 57335892 - PABPC1 chr8 100685816 100722809 - PCBP4 chr3 51957454 51974016 - RABGEF1 chr7 66682164 66811464 + GIMAP1-GIMAP5 chr7 150716668 150743646 + NDUFA2 chr5 140638740 140647785 - AGTPBP1 chr9 85546539 85742029 - TRA2B chr3 185914558 185938103 - UGT8 chr4 114598770 114678225 + VCL chr10 73995193 74121363 + SLC25A39 chr17 44319625 44324870 - AC027644.4 chr7 66628958 66811189 + DLX1 chr2 172084740 172089677 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1286 chr22 20249145 20249165 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC115284.1 chr3 51961212 51974031 - ZFAS1 chr20 49278178 49299600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.