exRNAdisease

Entry Detail

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General Information

Database ID: exR0428627 RNA Name: ABHD16A RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31686955 End Site(bp): 31703356 External Links: ENSG00000204427

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CBSL chr21 6444869 6468040 - FBXO45 chr3 196568611 196589059 + SENP6 chr6 75601509 75718281 + ZNF711 chrX 85244032 85273362 + WLS chr1 68098473 68233120 - RPA1 chr17 1829702 1900082 + ARID1B chr6 156776020 157210779 + GCN1 chr12 120127202 120194715 - FASTKD5 chr20 3146519 3159865 - VIPR1 chr3 42489299 42537573 + MRPL54 chr19 3762682 3768575 + RPL18 chr19 48615328 48619184 - CHD1 chr5 98853985 98928957 - TRAF4 chr17 28744005 28750956 + PTMS chr12 6765516 6770952 + FLNC chr7 128830377 128859274 + RAB1B chr11 66268590 66277492 + UCHL1 chr4 41256413 41268455 + CBS chr21 43053191 43076943 - NOL6 chr9 33461353 33473930 - TMEM50A chr1 25338317 25362361 + SLC39A1 chr1 153959099 153968184 - MAF chr16 79585843 79600737 - PACSIN2 chr22 42835412 43015149 - MOB2 chr11 1469457 1501247 - GJA1 chr6 121435595 121449727 + LIG3 chr17 34980512 35009743 + RPS27L chr15 63125872 63158021 - SLC25A28 chr10 99610522 99620609 - CCT7 chr2 73233420 73253021 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.