exRNAdisease

Entry Detail

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General Information

Database ID: exR0428629 RNA Name: ABHD17B RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 71862452 End Site(bp): 71910931 External Links: ENSG00000107362

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FBN2 chr5 128257909 128659185 - EIF4G2 chr11 10797050 10808940 - TXNDC12 chr1 52020131 52055191 - CSTF3 chr11 33077188 33162371 - GDI2 chr10 5765223 5842132 - VAT1 chr17 43014607 43025123 - PNRC2 chr1 23956839 23963462 + MDK chr11 46380756 46383837 + IBTK chr6 82169986 82247754 - TMPO chr12 98515512 98550379 + SRP9 chr1 225777813 225790468 + FBXL20 chr17 39252663 39402523 - TPX2 chr20 31739271 31801805 + SLC2A3 chr12 7919230 7936187 - DDX42 chr17 63773603 63819317 + SKA3 chr13 21153595 21176552 - PA2G4 chr12 56104537 56113910 + GOT2 chr16 58707131 58734342 - CENPV chr17 16342534 16353656 - TOMM7 chr7 22812628 22822852 - WBP4 chr13 41061509 41084006 + RPS9 chr19 54200809 54249003 + RPL37A chr2 216498825 216579180 + MT-CO2 chrMT 7586 8269 + MRPL43 chr10 100969458 100987515 - LAMA5 chr20 62307955 62367312 - VPS51 chr11 65089324 65111862 + GNAL chr18 11689264 11885685 + EEF1G chr11 62559596 62574086 - KLHDC2 chr14 49768130 49786385 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.