exRNAdisease

Entry Detail

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General Information

Database ID: exR0428632 RNA Name: ABHD2 RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 89087459 End Site(bp): 89202355 External Links: ENSG00000140526

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NUP210 chr3 13316235 13420322 - RPS21 chr20 62387103 62388520 + RPS6KB2 chr11 67428460 67435401 + MT-ND5 chrMT 12337 14148 + PPIF chr10 79347469 79355334 + BRD2 chr6 32968594 32981505 + MMD chr17 55392622 55421924 - AP3S2 chr15 89830599 89894638 - EEF1A1 chr6 73515750 73523797 - PABPC3 chr13 25095868 25099254 + MKRN1 chr7 140453033 140479536 - AC024592.3 chr19 5866171 5903787 - SHC2 chr19 416583 460996 - DMWD chr19 45782947 45792845 - RPUSD3 chr3 9837849 9844602 - PTGIS chr20 49503874 49568137 - METTL2A chr17 62423867 62450822 + EMC3 chr3 9962537 10011116 - NDUFA11 chr19 5891276 5904006 - KMT2D chr12 49018975 49059774 - CMTM3 chr16 66603874 66613892 + HLA-A chr6 29941260 29945884 + CWC27 chr5 64768930 65018750 + CCDC174 chr3 14651746 14672659 + ATP5F1A chr18 46080248 46104334 - RNF40 chr16 30761745 30776307 + MACF1 chr1 39081316 39487177 + HOXD4 chr2 176151550 176153226 + TSSC4 chr11 2400488 2403878 + SALL2 chr14 21521080 21537216 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-665 chr14 100875075 100875094 + hsa-miR-873-5p chr9 28888925 28888945 - hsa-miR-1294 chr5 154347153 154347174 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC104257.1 chr8 131308545 131317632 + AC079949.1 chr12 127142029 127146532 - MUC20-OT1 chr3 195658062 195739964 + SNAI3-AS1 chr16 88663298 88687278 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.