Entry Detail



General Information

Database ID:exR0428633
RNA Name:ABHD3
RNA Type:mRNA
Chromosome:chr18
Starnd:-
Coordinate:
Start Site(bp):21650901End Site(bp):21704780
External Links:ENSG00000158201



Disease Information

Disease Name:Pediatric TB meningitis
Disease Category:Infections
MeSH ID:D014390
Type:Diseases Category/Infections
Alias:Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Pediatric TB meningitis
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ELOB
chr16
2771414
2777297
-
FP565260.3
chr21
5022493
5040666
+
HNRNPK
chr9
83968083
83980616
-
ICOSLG
chr21
44217014
44240966
-
IRGQ
chr19
43584369
43596135
-
MTRNR2L12
chr3
96617188
96618236
-
NAA10
chrX
153929225
153935080
-
NOP53
chr19
47745546
47757058
+
ORC4
chr2
147930397
148021604
-
PEG10
chr7
94656325
94669695
+
POU3F3
chr2
104853287
104858574
+
RPL3
chr22
39312882
39320389
-
SATB2
chr2
199269500
199471266
-
SOS2
chr14
50117130
50231578
-
ZNF653
chr19
11483427
11505839
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.