exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428635 RNA Name: ABHD5 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 43690108 End Site(bp): 43734371 External Links: ENSG00000011198

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand KIAA1143 chr3 44737661 44761619 - RPLP1 chr15 69452814 69456205 + LGALS3BP chr17 78971238 78979947 - ATF7IP chr12 14365632 14502935 + TOMM22 chr22 38681957 38685421 + TIAF1 chr17 29073521 29078857 - TMSB4X chrX 12975110 12977227 + NIPSNAP1 chr22 29554808 29581327 - DCAF10 chr9 37800554 37867666 + ZFAT chr8 134477788 134713049 - THOC5 chr22 29505879 29555216 - CNN2 chr19 1026586 1039068 + GALNT2 chr1 230057990 230282122 + MYO18A chr17 29071124 29180412 - PLBD2 chr12 113358566 113391629 + HS3ST3B1 chr17 14301081 14349404 + TUBB4B chr9 137241287 137243707 + RPL18A chr19 17859910 17864153 + TUBB chr6 30720352 30725426 + AC010422.3 chr19 12643831 12648397 - CBSL chr21 6444869 6468040 - ATP5MC3 chr2 175176258 175184607 - CBS chr21 43053191 43076943 - ANO10 chr3 43354859 43691594 - ZNF75D chrX 135248920 135344109 - SEH1L chr18 12947133 12987536 + DICER1 chr14 95086228 95158010 - GDI1 chrX 154436913 154443467 + PTMA chr2 231706895 231713541 + HSD17B4 chr5 119452473 119637199 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand U73166.1 chr3 50260303 50263358 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.