exRNAdisease

Entry Detail

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General Information

Database ID: exR0428638 RNA Name: ABI1 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 26746593 End Site(bp): 26861087 External Links: ENSG00000136754

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand B2M chr15 44711487 44718877 + RPS27L chr15 63125872 63158021 - MTRNR2L1 chr17 22523111 22524663 + PSMB1 chr6 170535120 170553307 - COPG1 chr3 129249606 129277773 + TTF1 chr9 132375548 132406851 - TCEA1 chr8 53966552 54022456 - AGK chr7 141551278 141655244 + WAC chr10 28532493 28623112 + ACLY chr17 41866917 41930542 - SUMO3 chr21 44805617 44818779 - LARP1 chr5 154712843 154817605 + IL10RB chr21 33266367 33310187 + RNF125 chr18 32018825 32073219 + AFF1 chr4 86935002 87141054 + PTMS chr12 6765516 6770952 + UBE3C chr7 157138916 157269370 + THOP1 chr19 2785503 2815807 + SLC30A5 chr5 69093949 69131069 + KIF23 chr15 69414246 69448427 + PAN3 chr13 28138506 28295335 + CCT4 chr2 61868085 61888671 - BUB1 chr2 110637528 110678063 - MTHFD2 chr2 74198610 74217565 + ARID1A chr1 26693236 26782104 + TAF10 chr11 6606294 6612539 - MYO19 chr17 36495633 36543435 - SRRM2 chr16 2752626 2772538 + SRPK1 chr6 35832966 35921342 - RPLP1 chr15 69452814 69456205 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC091564.7 chr11 6610883 6616594 - AL158066.1 chr13 52167709 52291557 - AL355075.4 chr14 20343048 20343685 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.