exRNAdisease

Entry Detail

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General Information

Database ID: exR0428644 RNA Name: ABL2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 179099330 End Site(bp): 179229684 External Links: ENSG00000143322

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FBXL19 chr16 30923055 30948783 + AC010422.3 chr19 12643831 12648397 - SRPK2 chr7 105110704 105399308 - KIAA0753 chr17 6578147 6640711 - WDR74 chr11 62832342 62841809 - RPL11 chr1 23691742 23696835 + DNAH1 chr3 52316319 52400491 + APBB3 chr5 140558268 140564781 - HECTD4 chr12 112160188 112382439 - RPS3 chr11 75399515 75422280 + ARPP19 chr15 52547045 52569883 - INPPL1 chr11 72223701 72239147 + LRWD1 chr7 102464956 102473168 + KPNA5 chr6 116681187 116741867 + RPL12 chr9 127447674 127451406 - KMT2D chr12 49018975 49059774 - UGDH chr4 39498755 39528311 - ZC4H2 chrX 64915802 65034713 - PTMA chr2 231706895 231713541 + PDPN chr1 13583465 13617957 + CHCHD10 chr22 23765834 23768443 - FUCA2 chr6 143494812 143511720 - TEAD3 chr6 35473597 35497079 - HNRNPM chr19 8444767 8489114 + ABL1 chr9 130713016 130887675 + GLUL chr1 182381704 182392206 - UBR4 chr1 19074510 19210266 - SSR2 chr1 156009048 156020951 - RPL13A chr19 49487554 49492308 + IMP4 chr2 130342877 130347967 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-154-5p chr14 101059769 101059790 + hsa-miR-188-5p chrX 50003517 50003537 + hsa-miR-339-5p chr7 1022990 1023012 - hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-1224-5p chr3 184241405 184241423 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand HIPK1-AS1 chr1 113924000 113929495 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.