exRNAdisease

Entry Detail

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General Information

Database ID: exR0428645 RNA Name: ABLIM1 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 114431113 End Site(bp): 114768061 External Links: ENSG00000099204

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CDH1 chr16 68737292 68835541 + SMIM14 chr4 39546336 39638902 - SLC39A7 chr6 33200445 33204439 + COA6 chr1 234373456 234385068 + EEF2 chr19 3976056 3985463 - ZNF529 chr19 36534774 36605276 - PRRC2B chr9 131373636 131500197 + GAPDH chr12 6534512 6538374 + BTBD10 chr11 13388001 13463297 - EIF4B chr12 53006158 53042209 + MT-CO1 chrMT 5904 7445 + MT-ND1 chrMT 3307 4262 + CCNK chr14 99481169 99535044 + CRTAP chr3 33114014 33147773 + DDX47 chr12 12813316 12829981 + HSP90AA1 chr14 102080738 102139699 - MT-CO3 chrMT 9207 9990 + ACTR1A chr10 102461881 102502712 - HLA-B chr6 31269491 31357188 - EIF3E chr8 108201216 108435333 - BTG2 chr1 203305491 203309602 + RPS7 chr2 3575260 3580920 + P4HB chr17 81843161 81860624 - GNAI3 chr1 109548615 109600195 + TRIR chr19 12730640 12734684 - ANAPC11 chr17 81890790 81900991 + WBP11 chr12 14784582 14803486 - MRPS7 chr17 75261674 75266376 + ALAS1 chr3 52198086 52214327 + ZNF189 chr9 101398873 101410660 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3136-3p chr3 69048966 69048987 - hsa-miR-7111-3p chr6 35470558 35470579 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MAPKAPK5-AS1 chr12 111839764 111842902 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.