exRNAdisease

Entry Detail

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General Information

Database ID: exR0428651 RNA Name: ABRACL RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 139028745 End Site(bp): 139043302 External Links: ENSG00000146386

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FGFBP3 chr10 91906584 91909486 - RPL11 chr1 23691742 23696835 + STIL chr1 47250139 47314147 - BIRC6 chr2 32357028 32618899 + EIF4A1 chr17 7572706 7579006 + REPIN1 chr7 150368189 150374044 + UBE2I chr16 1308880 1327018 + UTP18 chr17 51260546 51297936 + EZR chr6 158765741 158819368 - RPS5 chr19 58386400 58394806 + NUCKS1 chr1 205712822 205750182 - APLP2 chr11 130068147 130144811 + POMT1 chr9 131502902 131523806 + DCLRE1B chr1 113905213 113914086 + MIF chr22 23894383 23895227 + CALR chr19 12938578 12944489 + XPO7 chr8 21919662 22006585 + GOT1 chr10 99396870 99430624 - TUBB chr6 30720352 30725426 + MEX3A chr1 156072013 156082465 - PXMP2 chr12 132687587 132704985 + BABAM1 chr19 17267376 17281249 + HSPB8 chr12 119178642 119221131 + PER1 chr17 8140472 8156506 - DHX32 chr10 125836337 125896436 - APP chr21 25880550 26171128 - SLC38A2 chr12 46358188 46372773 - NEDD9 chr6 11183298 11382348 - S100A16 chr1 153606886 153613145 - SENP3-EIF4A1 chr17 7563287 7578715 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-205-5p chr1 209432166 209432187 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AL035458.2 chr20 34234840 34281173 - AC135586.2 chr12 132688049 132714912 + AL359924.1 chr1 237862175 237928321 + AP006621.3 chr11 777578 784297 + MAPKAPK5-AS1 chr12 111839764 111842902 - NEAT1 chr11 65422774 65445540 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.