exRNAdisease

Entry Detail

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General Information

Database ID: exR0428652 RNA Name: ABRAXAS1 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 83459517 End Site(bp): 83523348 External Links: ENSG00000163322

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARF6 chr14 49893082 49897054 + ARHGAP11B chr15 30624494 30649529 + CEBPZ chr2 37201612 37231596 - CHD8 chr14 21385194 21456126 - CSDE1 chr1 114716913 114758676 - DYRK1A chr21 37365573 37526358 + DYRK3 chr1 206635536 206684419 + ETF1 chr5 138506095 138543236 - FADS2 chr11 61792980 61867354 + HELQ chr4 83407343 83455855 - KDM3A chr2 86440647 86492716 + PLEKHA5 chr12 19129752 19376400 + POU6F1 chr12 51186936 51217708 - PRDM4 chr12 107732871 107761272 - REXO4 chr9 133406059 133418096 - STK17B chr2 196133583 196176503 - TOMM20 chr1 235109341 235128837 - XRCC6 chr22 41621119 41664048 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.