exRNAdisease

Entry Detail

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General Information

Database ID: exR0428659 RNA Name: AC002996.1 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 111753890 End Site(bp): 111791418 External Links: ENSG00000257767

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACAD10 chr12 111686056 111757107 + ALDH2 chr12 111766887 111817532 + CDH3 chr16 68636189 68722616 + FGFR1 chr8 38400215 38468834 - GPT2 chr16 46884362 46931289 + IL32 chr16 3065297 3082192 + IPP chr1 45694324 45750653 - MT-ND2 chrMT 4470 5511 + NAP1L1 chr12 76036585 76084958 - PELI3 chr11 66466327 66477337 + PEX5 chr12 7188685 7218574 + PITPNM1 chr11 67491768 67506263 - RBM39 chr20 35701347 35742312 - RCC2 chr1 17406760 17439677 - RPS14 chr5 150442635 150449739 - SIKE1 chr1 114769479 114780685 - UBL7 chr15 74445977 74461182 - ZNF891 chr12 133106817 133130473 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.