exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428672 RNA Name: AC008758.1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 12461559 End Site(bp): 12551474 External Links: ENSG00000196826

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008758.6 chr19 12433103 12484816 - CALM1 chr14 90396502 90408268 + FAM72D chr1 145095974 145112696 + HLA-B chr6 31269491 31357188 - HSPA8 chr11 123057489 123063230 - NCOR2 chr12 124324415 124567589 - PAFAH1B1 chr17 2593210 2685615 + RPS8 chr1 44775251 44778779 + SDF4 chr1 1216908 1232067 - ZNF14 chr19 19710472 19733112 - ZNF443 chr19 12429706 12441021 - ZNF563 chr19 12317477 12333720 - ZNF564 chr19 12525373 12551542 - ZNF627 chr19 11559374 11619161 + ZNF791 chr19 12610918 12633840 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-23a-3p chr19 13836595 13836615 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008543.1 chr19 11639754 11686569 + RPARP-AS1 chr10 102449816 102461106 + ZNF433-AS1 chr19 11987617 12046275 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.