exRNAdisease

Entry Detail

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General Information

Database ID: exR0428677 RNA Name: AC010132.3 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 42909273 End Site(bp): 42932174 External Links: ENSG00000256646

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FAM83D chr20 38926312 38953106 + LRRC8A chr9 128882112 128918039 + MDFIC chr7 114922154 115019202 + LRRD1 chr7 92141643 92179531 - IGBP1 chrX 70133447 70166324 + FNBP1 chr9 129887187 130043194 - CKB chr14 103519667 103522833 - DDX39B chr6 31530219 31542448 - IPO5 chr13 97953658 98024296 + FAU chr11 65120630 65122177 - SLC25A20 chr3 48856926 48898904 - TOMM7 chr7 22812628 22822852 - RACK1 chr5 181236897 181248096 - ANP32E chr1 150218417 150236156 - MRPL30 chr2 99181152 99199561 + PRIMA1 chr14 93718298 93788485 - UBR5 chr8 102252273 102412759 - VDAC1 chr5 133971871 134004975 - FOXRED2 chr22 36487190 36507101 - ACTR2 chr2 65227753 65271253 + ZNF292 chr6 87152833 87265943 + AC009779.4 chr12 55716036 55724703 + VCL chr10 73995193 74121363 + RAB1A chr2 65070696 65130331 - SCD chr10 100347233 100364826 + GTF3C2 chr2 27325849 27357034 - PLP2 chrX 49171898 49175235 + GPI chr19 34359480 34402413 + MAF1 chr8 144104461 144107611 + PCMT1 chr6 149749443 149811420 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC104257.1 chr8 131308545 131317632 + ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - LOXL1-AS1 chr15 73908071 73928248 - WAC-AS1 chr10 28522652 28533066 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.