exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428689 RNA Name: AC020915.5 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 58228914 End Site(bp): 58315183 External Links: ENSG00000283515

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GPATCH11 chr2 37084451 37099244 + ERVK3-1 chr19 58305319 58315663 + ZNF586 chr19 57769655 57819939 + AC067968.1 chr19 44025354 44087318 + SPART chr13 36301638 36370180 - ZNF805 chr19 57240632 57262728 + VPS4A chr16 69311350 69326939 + TEX264 chr3 51662693 51704323 + NBEAL2 chr3 46979666 47009704 + SNU13 chr22 41673933 41690504 - ZNF264 chr19 57191500 57222846 + SNX11 chr17 48103357 48123074 + ZNF460 chr19 57280051 57294069 + ARL2-SNX15 chr11 65014182 65040570 + ZNF689 chr16 30602558 30624012 - ALDH6A1 chr14 74056847 74084492 - CHMP3 chr2 86503430 86563479 - GSE1 chr16 85169525 85676204 + AC003002.3 chr19 57389884 57419994 + HSPA1B chr6 31827738 31830254 + ARL2 chr11 65014160 65022184 + MAN2B1 chr19 12646511 12666742 - HVCN1 chr12 110627841 110704950 - ZNF584 chr19 58401504 58418327 + ZNF888 chr19 52904417 52923481 - HLA-DPA1 chr6 33064569 33080775 - HAUS5 chr19 35612735 35625355 + NETO1 chr18 72742314 72868146 - TMEM94 chr17 75441159 75500452 + SND1 chr7 127652194 128092609 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC092364.1 chr19 21768772 21793860 - AC132217.1 chr11 2129121 2129964 - AC020915.1 chr19 58278966 58315197 + PRKCQ-AS1 chr10 6580419 6616921 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.