exRNAdisease

Entry Detail

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General Information

Database ID: exR0428693 RNA Name: AC022384.1 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 10249372 End Site(bp): 10285796 External Links: ENSG00000272410

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCT4 chr2 61868085 61888671 - TATDN2 chr3 10248023 10281218 + KAT2A chr17 42113111 42121367 - FGFRL1 chr4 1009936 1026898 + ERI1 chr8 9002147 9116746 + TEX264 chr3 51662693 51704323 + MT-CYB chrMT 14747 15887 + ATP2C1 chr3 130850595 131016712 + UBE2D3 chr4 102794383 102868896 - SDK1 chr7 3301252 4269000 + PSMB3 chr17 38752741 38764225 + MAEA chr4 1289887 1340147 + AGO4 chr1 35808016 35857890 + CCL22 chr16 57358783 57366189 + CCDC43 chr17 44673069 44689779 - RPS8 chr1 44775251 44778779 + KDELR1 chr19 48382575 48391551 - FAM13B chr5 137937960 138051961 - ACTB chr7 5527148 5563784 - CHTOP chr1 153633982 153646306 + GAPVD1 chr9 125261794 125367207 + MCM3 chr6 52264014 52284881 - MRM3 chr17 782353 792509 + HSP90AB1 chr6 44246166 44253888 + WDR54 chr2 74421678 74425755 + MED1 chr17 39404285 39451272 - PIM2 chrX 48913182 48919024 - PKD1 chr16 2088708 2135898 - PELP1 chr17 4669774 4704337 - SUPT16H chr14 21351476 21384019 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG14 chr15 24978583 25420336 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.