exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428700 RNA Name: AC040162.1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 67929614 End Site(bp): 67936017 External Links: ENSG00000261884

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SLC29A1 chr6 44219553 44234142 + RPS5 chr19 58386400 58394806 + EDC4 chr16 67873052 67884499 + TEAD2 chr19 49340595 49362457 - TSR2 chrX 54440404 54448032 + EEF1G chr11 62559596 62574086 - AC120057.2 chr17 7240427 7244635 - C7orf50 chr7 996986 1138260 - MEF2D chr1 156463727 156500779 - BAG6 chr6 31639028 31652705 - COX7C chr5 86617928 86620962 + GOLPH3 chr5 32124716 32174319 - POU2AF1 chr11 111352255 111455630 - SPIN1 chr9 88388430 88478694 + SPG21 chr15 64963022 64990310 - AC090360.1 chr18 80034346 80097088 + UBE2F-SCLY chr2 237967014 238099412 + TRAPPC4 chr11 119018763 119025454 + RSBN1 chr1 113761832 113812476 - ACTG1 chr17 81509971 81523847 - P2RY8 chrX 1462581 1537185 - ADAR chr1 154582057 154628013 - CIB2 chr15 78104606 78131535 - PWP1 chr12 107685799 107713162 + UBE2F chr2 237966827 238042782 + UNC119B chr12 120710458 120723640 + SMC1A chrX 53374149 53422728 - RPS6 chr9 19375715 19380236 - INTS14 chr15 65578753 65611289 - EEF1A1 chr6 73515750 73523797 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005632.3 chr16 21626742 21627569 + AC087854.1 chr8 22481588 22553444 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.