exRNAdisease

Entry Detail

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General Information

Database ID: exR0428708 RNA Name: AC069503.2 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 121888809 End Site(bp): 121921470 External Links: ENSG00000256950

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPL13A chr19 49487554 49492308 + RILPL2 chr12 123410683 123436717 - GART chr21 33503931 33543491 - ACTG1 chr17 81509971 81523847 - CALR chr19 12938578 12944489 + CPNE7 chr16 89575758 89597246 + TRIM22 chr11 5689697 5737089 + PSMD2 chr3 184299198 184309050 + PLEKHA7 chr11 16777297 17014414 - ACAD8 chr11 134253495 134265855 + SNRPA chr19 40750637 40765389 + TSPAN33 chr7 129144707 129169699 + PSMB7 chr9 124353465 124415444 - HLA-B chr6 31269491 31357188 - LONP1 chr19 5691834 5720572 - PNMA8A chr19 46466491 46471563 - LAPTM5 chr1 30732469 30757774 - ZPR1 chr11 116773799 116788039 - ZBTB7A chr19 4043303 4066899 - KDELR1 chr19 48382575 48391551 - LMOD1 chr1 201896456 201946588 - RPL30 chr8 98024851 98046469 - LSR chr19 35248330 35267964 + TBC1D14 chr4 6909242 7033118 + RPL11 chr1 23691742 23696835 + PTGES3 chr12 56663341 56688408 - CKB chr14 103519667 103522833 - NUP205 chr7 135557917 135648757 + PSMD9 chr12 121888732 121918297 + RPS2 chr16 1962058 1964841 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC01572 chr16 72236281 72665014 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.