exRNAdisease

Entry Detail

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General Information

Database ID: exR0428727 RNA Name: AC118549.1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 77562416 End Site(bp): 77683419 External Links: ENSG00000036549

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HLA-B chr6 31269491 31357188 - RAB23 chr6 57186992 57222307 - LARGE1 chr22 33162226 33922841 - PPP6R1 chr19 55229779 55259017 - SNF8 chr17 48929316 48944842 - MTRNR2L8 chr11 10507894 10509186 - CMIP chr16 81445170 81711762 + AC099811.2 chr17 42119674 42154916 - CAPZB chr1 19338775 19485539 - DPY30 chr2 31867809 32039805 - CDC25C chr5 138285265 138338355 - HMGB3 chrX 150980509 150990771 + DDOST chr1 20651767 20661544 - CMTM6 chr3 32481312 32502852 - TMEM209 chr7 130164713 130207770 - SH3GLB2 chr9 129007036 129028303 - CD63 chr12 55725323 55729707 - PABPC1 chr8 100685816 100722809 - UBE2E1 chr3 23805955 23891640 + POU3F2 chr6 98834574 98839458 + ADAT2 chr6 143422832 143450695 - SREBF2 chr22 41833079 41907307 + ZNF133 chr20 18288283 18316996 + ZC3H18 chr16 88570381 88631966 + GFRA1 chr10 116056925 116273467 - AREL1 chr14 74653437 74713108 - ZFP36L1 chr14 68787660 68796253 - KCTD14 chr11 78015715 78046191 - RAB5C chr17 42124976 42155044 - ASAH1 chr8 18055992 18084998 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008738.2 chr19 33305036 33309387 + AL160236.2 chr14 60879714 60982585 + PSMA3-AS1 chr14 58265365 58298134 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.