Entry Detail



General Information

Database ID:exR0428730
RNA Name:AC134669.1
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):31305213End Site(bp):31318831
External Links:ENSG00000265118



Disease Information

Disease Name:Pediatric TB meningitis
Disease Category:Infections
MeSH ID:D014390
Type:Diseases Category/Infections
Alias:Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Pediatric TB meningitis
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EGLN3
chr14
33924227
34462774
-
EIF2S3B
chr12
10505602
10523135
+
ELAVL1
chr19
7958573
8005659
-
EVI2A
chr17
31317560
31321884
-
EVI2B
chr17
31303770
31314105
-
JRKL
chr11
96389989
96507574
+
LSM2
chr6
31797396
31806966
-
MTRNR2L1
chr17
22523111
22524663
+
RPL19
chr17
39200283
39204732
+
TAP1
chr6
32845209
32853978
-
TBPL1
chr6
133952170
133990432
+
VOPP1
chr7
55436056
55572988
-
ZSCAN21
chr7
100049774
100065040
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZFAS1
chr20
49278178
49299600
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.