Entry Detail



General Information

Database ID:exR0428733
RNA Name:AC138894.1
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):28456371End Site(bp):28492098
External Links:ENSG00000261832



Disease Information

Disease Name:Pediatric TB meningitis
Disease Category:Infections
MeSH ID:D014390
Type:Diseases Category/Infections
Alias:Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Pediatric TB meningitis
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SAT1
chrX
23783173
23786226
+
METTL3
chr14
21498133
21511342
-
NPIPA1
chr16
14922802
14952060
+
CCDC51
chr3
48432164
48440456
-
AC138969.1
chr16
16317444
16350590
+
ZSWIM8
chr10
73785582
73801797
+
NPIPA8
chr16
18317942
18336736
-
CPSF1
chr8
144393229
144409335
-
USP48
chr1
21678298
21783606
-
NPIPB6
chr16
28342555
28363508
-
KIAA0556
chr16
27550133
27780369
+
NPIPB12
chr16
29483642
29505999
-
ADD2
chr2
70607618
70768225
-
ACTB
chr7
5527148
5563784
-
NPIPB5
chr16
22479121
22536521
+
KDM5A
chr12
280057
389320
-
MROH1
chr8
144148016
144261940
+
RPL36
chr19
5674947
5691875
+
SUPT5H
chr19
39436156
39476670
+
HNRNPA1
chr12
54280193
54287088
+
HNRNPA1P48
chr16
51553436
51647132
+
TUBB2B
chr6
3224277
3231730
-
AP3D1
chr19
2100988
2164468
-
FREM2
chr13
38687077
38887131
+
MAP3K5
chr6
136557046
136792477
-
TUBA1B
chr12
49127782
49131397
-
MMS19
chr10
97458324
97498794
-
AGPAT3
chr21
43865223
43987592
+
MED24
chr17
40019097
40061215
-
TBC1D15
chr12
71839707
71927248
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MALAT1
chr11
65497688
65506516
+
RRN3P2
chr16
29074976
29116718
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.