exRNAdisease

Entry Detail

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General Information

Database ID: exR0428738 RNA Name: AC244197.3 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 149477104 End Site(bp): 149540926 External Links: ENSG00000241489

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand POLR3E chr16 22297375 22335101 + YWHAB chr20 44885702 44908532 + TAF7 chr5 141260225 141320784 - ATP5F1A chr18 46080248 46104334 - FNBP4 chr11 47716494 47767443 - FCMR chr1 206903317 206923247 - PFN1 chr17 4945652 4949061 - RAB5B chr12 55973913 55996683 + CBR1 chr21 36069941 36073166 + IDS chrX 149476988 149521096 - ICE1 chr5 5420664 5490220 + CYP51A1 chr7 92112153 92134803 - PMPCB chr7 103297435 103329511 + AL138752.2 chr9 37588413 38068687 - SAFB chr19 5623035 5668478 + LRRD1 chr7 92141643 92179531 - EIF4H chr7 74174245 74197101 + FMNL1 chr17 45221444 45247319 + SLC30A9 chr4 41990502 42090461 + STRBP chr9 123109500 123268586 - XRCC5 chr2 216107464 216206303 + AL513165.2 chr9 37512547 37592469 - ZNF589 chr3 48241100 48299253 + NBEAL1 chr2 203014879 203226378 + CSNK2B chr6 31665236 31670343 + B2M chr15 44711487 44718877 + EEF1D chr8 143579697 143599541 - ISLR2 chr15 74100311 74138540 + PRPF8 chr17 1650629 1684867 - SLC7A7 chr14 22773222 22829820 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC135178.2 chr17 8318088 8318712 - LINC00894 chrX 149938613 150224580 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.