exRNAdisease

Entry Detail

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General Information

Database ID: exR0428743 RNA Name: ACAD10 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 111686056 End Site(bp): 111757107 External Links: ENSG00000111271

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NDUFA10 chr2 239892450 240025345 - GPCPD1 chr20 5544439 5611006 - IPP chr1 45694324 45750653 - MRM2 chr7 2234195 2242205 - SLAMF6 chr1 160485030 160523262 - MYH9 chr22 36281277 36388067 - SLC52A2 chr8 144354135 144361272 + CPT1C chr19 49690898 49713731 + PSMD11 chr17 32444379 32483319 + HMGB2 chr4 173331376 173334432 - SP110 chr2 230167293 230225729 - CBX3 chr7 26201162 26213607 + DNAJC25 chr9 111631334 111654351 + PTP4A3 chr8 141391995 141432454 + CMTR1 chr6 37433219 37482827 + PLXNA1 chr3 126988594 127037392 + ZBED4 chr22 49853844 49890080 + ST8SIA1 chr12 22063773 22437041 - ACTN1 chr14 68874143 68979440 - UBE2Z chr17 48908407 48929056 + GRK2 chr11 67266473 67286556 + DCTN2 chr12 57530102 57547331 - FOXM1 chr12 2857681 2877155 - MT-ND1 chrMT 3307 4262 + VIPAS39 chr14 77426675 77457952 - EPM2AIP1 chr3 36985043 36993131 - ST6GAL1 chr3 186930502 187078553 + TPGS2 chr18 36777647 36829216 - AL132780.3 chr14 22946270 22982258 - FSCN3 chr7 127591409 127602144 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.