Entry Detail



General Information

Database ID:exR0428744
RNA Name:ACAD11
RNA Type:mRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):132558138End Site(bp):132660082
External Links:ENSG00000240303



Disease Information

Disease Name:Pediatric TB meningitis
Disease Category:Infections
MeSH ID:D014390
Type:Diseases Category/Infections
Alias:Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Pediatric TB meningitis
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NPHP3-ACAD11
chr3
132558142
132722459
-
BET1L
chr11
167784
207428
-
P4HB
chr17
81843161
81860624
-
STIM1
chr11
3854527
4093210
+
HLA-DQA1
chr6
32628179
32647062
+
FAR1
chr11
13668668
13732346
+
PUM2
chr2
20248691
20352234
-
TCIRG1
chr11
68039025
68050895
+
PIK3C2A
chr11
17077730
17207983
-
PRPF8
chr17
1650629
1684867
-
RPS8
chr1
44775251
44778779
+
HADH
chr4
107989714
108035175
+
ZNF311
chr6
28994785
29005316
-
MDN1
chr6
89642498
89819794
-
PPOX
chr1
161166056
161178013
+
CD52
chr1
26317958
26320523
+
RPL12
chr9
127447674
127451406
-
PMF1
chr1
156212993
156240042
+
HSPA9
chr5
138553756
138575416
-
SH3PXD2B
chr5
172325000
172454525
-
CACNA2D3
chr3
54122547
55074557
+
TK1
chr17
78174091
78187233
-
DNAJB1
chr19
14514769
14529770
-
ATP5IF1
chr1
28236109
28246906
+
NBDY
chrX
56729241
56819179
+
RABGAP1L
chr1
174159410
174995308
+
ZNF146
chr19
36214602
36238774
+
EHMT2
chr6
31879759
31897687
-
SGTB
chr5
65665928
65723035
-
MTHFD2
chr2
74198610
74217565
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.