exRNAdisease

Entry Detail

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General Information

Database ID: exR0428745 RNA Name: ACAD8 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 134253495 End Site(bp): 134265855 External Links: ENSG00000151498

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CALR chr19 12938578 12944489 + PPA1 chr10 70202835 70233911 - YBX1 chr1 42682418 42703805 + COMMD1 chr2 61888724 62147247 + DCTD chr4 182890060 182917936 - NCK1 chr3 136862208 136951606 + SOS1 chr2 38981549 39124345 - MT-CO3 chrMT 9207 9990 + GSTP1 chr11 67583742 67586656 + PTPRCAP chr11 67435510 67437682 - GTF2A2 chr15 59638062 59657541 - ZNF585B chr19 37181579 37218153 - PGM2 chr4 37826660 37862937 + TBC1D2B chr15 77984036 78077724 - RPS27A chr2 55231903 55235853 + SMARCB1 chr22 23786931 23838008 + MZT2A chr2 131464900 131492743 - CORO1B chr11 67435510 67443821 - SEC62 chr3 169966635 169998373 + TRIM71 chr3 32817997 32897824 + PSMD9 chr12 121888732 121918297 + CCDC86 chr11 60842113 60851081 + PBX1 chr1 164555584 164899296 + VPS26B chr11 134224671 134247788 + ATRAID chr2 27212027 27217178 + EEF1G chr11 62559596 62574086 - PODXL chr7 131500262 131558217 - RPL29 chr3 51993522 51995895 - ISG15 chr1 1001138 1014540 + PDP1 chr8 93857807 93926068 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand BOLA3-AS1 chr2 74148007 74151952 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.