exRNAdisease

Entry Detail

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General Information

Database ID: exR0428746 RNA Name: ACAD9 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 128879596 End Site(bp): 128916067 External Links: ENSG00000177646

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP5F1E chr20 59025475 59032345 - AC138811.2 chr16 18788063 18801519 - GNA12 chr7 2728105 2844308 - MAVS chr20 3846799 3876123 + TGS1 chr8 55773446 55826445 + RPS4X chrX 72255679 72277248 - CABIN1 chr22 24011192 24178628 + SLC30A9 chr4 41990502 42090461 + SRSF7 chr2 38743599 38751494 - RPS13 chr11 17074388 17077715 - MIB2 chr1 1615415 1630610 + EDARADD chr1 236348257 236502915 + ARFIP1 chr4 152779937 152918463 + EI24 chr11 125569280 125584684 + RPS25 chr11 119015712 119018691 - GTF3C2 chr2 27325849 27357034 - ATP6V1F chr7 128862856 128865847 + SLC36A1 chr5 151437046 151492379 + RBMX chrX 136848004 136880764 - MT-ND2 chrMT 4470 5511 + B2M chr15 44711487 44718877 + TOB1 chr17 50862223 50867978 - ZNF551 chr19 57681969 57717301 + PEBP1 chr12 118136124 118145584 + ATP5MC2 chr12 53632726 53677408 - EEF2 chr19 3976056 3985463 - VIPAS39 chr14 77426675 77457952 - SLC18A2 chr10 117241093 117279430 + MID1IP1 chrX 38801432 38806537 + SNRNP200 chr2 96274338 96321271 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.