exRNAdisease

Entry Detail

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General Information

Database ID: exR0428749 RNA Name: ACADS RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 120725774 End Site(bp): 120740008 External Links: ENSG00000122971

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004832.3 chr22 30409255 30428990 + AP002990.1 chr11 62559603 62591531 - CD52 chr1 26317958 26320523 + CHD4 chr12 6570082 6614524 - CYSTM1 chr5 140175156 140282052 + DNAJC5 chr20 63895126 63936031 + EEF1G chr11 62559596 62574086 - EIF2B1 chr12 123620406 123633766 - EIF3J chr15 44537125 44563029 + EIF5AL1 chr10 79512601 79516440 + GPAT2 chr2 96021946 96039451 - HNRNPA2B1 chr7 26173057 26201529 - IMP3 chr15 75639085 75648706 - LRRK1 chr15 100919327 101078257 + MCM7 chr7 100092728 100101940 - MLH1 chr3 36993350 37050846 + MTFP1 chr22 30425623 30429054 + PFKL chr21 44300051 44327376 + PIP4K2C chr12 57591174 57603418 + PPP2R1A chr19 52190048 52229518 + RPLP1 chr15 69452814 69456205 + RPS3 chr11 75399515 75422280 + SMAD7 chr18 48919853 48952052 - STIM1 chr11 3854527 4093210 + TBX3 chr12 114670255 114684175 - TPI1 chr12 6867119 6870948 + TUBB chr6 30720352 30725426 + UNC119B chr12 120710458 120723640 + VCP chr9 35056064 35072627 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.