exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428751 RNA Name: ACADVL RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 7217125 End Site(bp): 7225266 External Links: ENSG00000072778

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand VKORC1 chr16 31090842 31095980 - EIF2S1 chr14 67360151 67386516 + OAF chr11 120211032 120230334 + TXN2 chr22 36467046 36481640 - LRRC8A chr9 128882112 128918039 + ALKBH4 chr7 102456238 102464863 - IGF2BP2 chr3 185643739 185825056 - TMED7 chr5 115613210 115632992 - ZNF782 chr9 96816269 96875623 - RRP1B chr21 43659560 43696079 + ERI3 chr1 44221070 44355260 - RAN chr12 130872037 130877678 + PXDN chr2 1631887 1744852 - PLEKHG4B chr5 92151 189972 + B2M chr15 44711487 44718877 + RBM8A chr1 145917714 145927678 - ZNRF2 chr7 30284597 30367689 + SLC29A1 chr6 44219553 44234142 + CANX chr5 179678628 179731641 + ZFP36L1 chr14 68787660 68796253 - RBM23 chr14 22893204 22919182 - EMP3 chr19 48321509 48330553 + WDSUB1 chr2 159235793 159286799 - GSTP1 chr11 67583742 67586656 + FAM102A chr9 127940582 127980989 - UQCRHL chr1 15807169 15809348 - CD70 chr19 6583183 6604103 - GOPC chr6 117560269 117602542 - RIPOR1 chr16 67518418 67546788 + POLDIP3 chr22 42583721 42614962 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC098850.4 chr17 16788057 16816540 + AD000090.1 chr19 35557956 35581954 + PCAT14 chr22 23536881 23547797 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.