exRNAdisease

Entry Detail

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General Information

Database ID: exR0428755 RNA Name: ACAP3 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 1292390 End Site(bp): 1309609 External Links: ENSG00000131584

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand IMP3 chr15 75639085 75648706 - TAOK2 chr16 29973868 29992261 + SDCBP chr8 58552924 58582859 + NUP62 chr19 49906825 49929763 - ALG1 chr16 5033923 5087379 + EEF2 chr19 3976056 3985463 - S100A13 chr1 153618787 153631360 - RUNX3 chr1 24899511 24965121 - SLC15A4 chr12 128793194 128823958 - HAND1 chr5 154474972 154478227 - MTOR chr1 11106535 11262551 - SENP3 chr17 7561919 7571969 + MIF chr22 23894383 23895227 + SLC7A5 chr16 87830023 87869507 - MT-ND4 chrMT 10760 12137 + DEPDC5 chr22 31753867 31908033 + SLC27A2 chr15 50182196 50236385 + XPO6 chr16 28097979 28211920 - PCSK1N chrX 48831096 48835610 - KMT2B chr19 35717973 35738878 + MCM3AP chr21 46235133 46286297 - PFKM chr12 48105139 48146404 + TUBA4A chr2 219249710 219278170 - CLTC chr17 59619689 59696956 + PIK3C2B chr1 204422628 204494724 - TRIM7 chr5 181193924 181205293 - HIRA chr22 19330698 19447450 - AURKAIP1 chr1 1373730 1375495 - SETD1A chr16 30957754 30984664 + ZFHX4 chr8 76681239 76867281 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL157392.3 chr10 13631143 13668445 + AL355075.4 chr14 20343048 20343685 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.