exRNAdisease

Entry Detail

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General Information

Database ID: exR0428757 RNA Name: ACAT2 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 159762045 End Site(bp): 159779112 External Links: ENSG00000120437

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RIMS3 chr1 40620680 40665682 - RPL13 chr16 89560657 89566828 + ATP5MC2 chr12 53632726 53677408 - TTF2 chr1 117060326 117107453 + FAM83F chr22 39994954 40043534 + TMEM14C chr6 10722915 10731129 + PWP2 chr21 44107373 44131181 + CINP chr14 102341102 102362916 - FKBP8 chr19 18531751 18544077 - PFN1 chr17 4945652 4949061 - HDAC11 chr3 13479724 13506424 + RIOX1 chr14 73490933 73493394 + HSF1 chr8 144291591 144314720 + SLC7A3 chrX 70925579 70931125 - RPS13 chr11 17074388 17077715 - ALG12 chr22 49900229 49918438 - SKIL chr3 170357678 170396835 + BTG1 chr12 92140278 92145846 - FDPS chr1 155308748 155320666 + ZCCHC10 chr5 132996985 133026604 - IFT27 chr22 36758202 36776256 - SURF2 chr9 133356550 133361158 + COX6B1 chr19 35648323 35658782 + ZNF451 chr6 57086844 57170305 + RPL30 chr8 98024851 98046469 - MLYCD chr16 83899115 83951445 + HAUS4 chr14 22946228 22957161 - RPL37 chr5 40825262 40835222 - MTRNR2L11 chr1 237943724 237945275 - KDM4A chr1 43650149 43705518 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL158835.3 chr10 125707416 125749525 - HCP5 chr6 31463170 31478936 + PRNCR1 chr8 127079874 127092600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.